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This tutorial introduces how to use the Illinois Campus Cluster to run scientific application code. It begins with a lesson on the fundamental concepts of scientific computing on a High-Performance Computing (HPC) cluster. The tutorial then progresses through how-to access the Illinois Campus Cluster, manage files, edit files, setup your software environment, and transfer files. Finally, you will complete a hands-on exercise where you will run an example application. Even if you are not a Campus Cluster user, you can still learn a lot from this tutorial about using an HPC cluster for scientific computing.